Auto-brewery syndrome – a rare condition where the body brews its own alcohol.

"Looking Into My Dreams, Awilda," is one of four large-scale portrait sculptures titled "Jamue Plensa: 1004 Portraits," in Millennium Park, Chicago. (Dr. Noorali Bharwani)
"Looking Into My Dreams, Awilda," is one of four large-scale portrait sculptures titled "Jamue Plensa: 1004 Portraits," in Millennium Park, Chicago. (Dr. Noorali Bharwani)

It was reported on CNN and now it is making rounds in the media. A woman in upstate New York was charged with DUI (driving under the influence) hours after her last drink.

The lady blew a blood alcohol level of nearly 0.40. The police procedure is to take the accused to a hospital, as that level is considered extremely life threatening.
The lady’s blood alcohol level in the hospital was 0.30. This was many hours after her last drink.

The lady was charged with DUI but a judge dismissed the charge after being presented with evidence the woman suffered from “auto-brewery syndrome.”

“I’m in touch with about 30 people who believe they have this same syndrome, about 10 of them are diagnosed with it,” says Panola College Dean of Nursing Barbara Cordell, who has studied the syndrome for years. “They can function at alcohol levels such as 0.30 and 0.40 when the average person would be comatose or dying. Part of the mystery of this syndrome is how they can have these extremely high levels and still be walking around and talking.” Cordell was quoted on CNN.

The condition is also known as gut-fermentation syndrome. This rare medical condition can occur when abnormal amounts of yeast in the gut convert common food carbohydrates into alcohol. The process is believed to take place in the small bowel.

The condition was first described in 1912 as “germ carbohydrate fermentation.” Since then, from time to time, it has surfaced in the media. In 2013, a case of a 61-year-old man who had frequent bouts of unexplained drunkenness for years was documented. Subsequently, he was diagnosed with an intestinal overabundance of Saccharomyces cerevisiae, or brewer’s yeast, the same yeast used to make beer.

CNN report says that the lady is treating her condition with anti-fungal medications and a yeast-free diet with absolutely no sugar, no alcohol and very low carbs. The report says that this does not work for everybody.

So I looked it up on Wikipedia.

The condition has been described variously. The self-brewery syndrome, intestinal fermentation syndrome, and gut syndrome fermentation is an intestinal disease and very poorly documented. There is no consensus among specialists.

The condition was described for the first time in 1976 in Japan. One case went unnoticed for 20 years, despite strong alcoholic intoxication following meals high in sugar or high in carbohydrates.

Symptoms of the disease can have a significant impact on daily life, says Wikipedia.  Recurrent symptoms such as dizziness, dry mouth, cold sweats, hangover, disorientation, irritable bowel syndrome, chronic fatigue syndrome, which can lead to other health problems such as depression and anxiety.

Is there a good treatment for it?

In general, the effects of the condition can be alleviated with a very low carbohydrate diet. The antifungal drug, fluconazole, can be an effective treatment against the disease since the drug is able to reduce Saccharomyces cerevisiae, responsible for fermentation in the gastrointestinal tract.

If you think you are suffering from auto-brewery syndrome, then to put it simply, don’t eat and drive.

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Paternity Test: Is it reliable?

Justin Bieber took a DNA test last week in New Jersey. He wants to refute the claims of a San Diego woman who filed a paternity suit against Bieber. The suit has since been withdrawn, but Bieber’s legal team intends to sue the accuser, Mariah Yeater, in order to discourage future baseless claims.

Yeater is 20. She had claimed that she had sex backstage with the 17-year-old last year and that he was the father of her baby, born in July. She was demanding child support. Bieber has denied the allegation.

Yeater may face charge of statutory rape since the singer was only 16 years old at the time of the alleged sexual encounter.

What is paternity test?

I went to Wikipedia to look for an answer. A paternity test establishes genetic proof as to whether a man is the biological father of an individual. A maternity test establishes whether a woman is the biological mother of an individual. Currently, genetic testing is the most reliable standard. It is the most advanced and accurate technology to determine parentage.

In a DNA parentage test, the result (called the probability of parentage) is zero per cent if the alleged parent is not biologically related to the child. The probability of parentage is typically greater than 99.9 per cent when the alleged parent is biologically related to the child, says the Wiki article.

Almost all individuals have a single and distinct set of genes. Rarely, individuals, known as “chimeras”, have at least two different sets of genes. There have been several cases of DNA profiling that falsely “proved” that a mother was unrelated to her children.

A person’s DNA is created from DNA (genetic material) of both parents in roughly equal numbers. A person’s DNA is a unique combination of genetic material in a new cell. This genetic material is known as the nuclear genome of the individual, because it is found in the nucleus.

Comparing the DNA sequence of an individual to that of another individual can show whether one of them was derived from the other. The mitochondria in the cells also have their own genetic material termed the mitochondrial genome. Mitochondrial DNA comes only from the mother.

Proving a relationship based on comparison of the mitochondrial genome is much easier than that based on the nuclear genome. However, testing the mitochondrial genome can prove only if two individuals are related through maternal descent. This is of limited value. It could not be used to test for paternity.

Nuclear DNA can accurately identify the father and the mother, and is the most common material used in parentage testing.

Several laboratories across Canada provide paternity testing. There are many ways to collect specimens for the test. For the test to be legally binding, one has to follow strict guidelines to prevent fraud. The sample is sealed in tamper-evident packaging. The least invasive and most common form of paternity testing uses the buccal (lining of the mouth) swab. This consists of a special swab, similar to a cotton-tipped swab. The swab is rubbed against the inside of the cheek to collect loose cells to be used for testing. One can also use a blood sample.

To ensure the identities of the parties involved, participants must produce a government issued ID. They will also be photographed. DNA can also be collected from the baby before birth. Amniocentesis can be performed between the 14th and 20th weeks of pregnancy.
A chorionic villus sample is obtained by inserting a thin needle into the vagina to collect tissue.

The cost for paternity testing varies widely, depending on which type of test is chosen. The cost of a buccal swab test collected at a facility is around $500, plus the charge for collection. For pre-natal testing, there may be an additional fee.

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