Synthetic Hallucinating Designer Drugs are Not Synthetic Marijuana

A lake in Kananaskis to relax and unwind. Better than smoking weed.
A lake in Kananaskis to relax and unwind. Better than smoking weed.

Naturally growing cannabis (marijuana) is a popular psychoactive plant that is often used recreationally. Use of marijuana is in the news almost every day. Not to mention the recent death of a very accomplished actor. Cannabis is also unique in that it contains a psychoactive substance, THC. In some jurisdictions, it is legal to use medical cannabis to treat pain, insomnia, and stimulate appetite.

Then there is “synthetic” cannabis, a psychoactive designer drug created by spraying natural herbs with synthetic chemicals that, when consumed, produce psychoactive effects similar to the effects of cannabis. According to Wikipedia, synthetic cannabis are often known by the brand names K2 and Spice. “Synthetic” is considered a misnomer, because the ingredients contained in these products are mimics, not copies.

An article in the Canadian Medical Association Journal (Five things to know about synthetic cannabinoids, February 18, 2014) says, “Synthetic cannabinoids are not synthetic marijuana.” They are a large family of chemically unrelated compounds functionally similar to delta-9-tetrahydrocannabinol (THC), the active component of Cannabis sativa. It is important to remember, synthetic cannabinoids are NOT derived from cannabis.

The article says the use of synthetic cannabinoids is increasing, quoting statistics from the American Association of Poison Control Centers. The typical users are adolescent males and young men in their early to mid-20s, with the most commonly stated reasons for use being curiosity, relaxation and attaining the desired effects of THC while avoiding toxicological detection. Synthetic cannabinoids cannot be legally sold in Canada.

Use of synthetic cannabinoid can cause psychosis, agitation, seizures, acute kidney injury, low potassium level, high blood pressure, increased heart rate, heart attack and death. Clinical diagnosis of synthetic cannabinoids overdose is difficult to make in a patient presenting with acute psychosis unless there is a high index of suspicion.

There is no specific antidote.

So, it boils down to the same old adage, “Prevention is better than cure.” There are so many wonderful things to do in life that one wonders what drives people to drugs, smoking and drinking. I guess we are all not made of the same outlook in life. People in the same family, carrying similar genes, sometimes end up in different directions. There are so many genetic and environmental factors over which we have no control. That does not mean we should not try and be healthy and make the best of what we have been given and improve on it.

You can be what you want to be. Keep smiling. Talk to you again soon.

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Widely Admired Actor Dies from Apparent Heroin Overdose

The world's tallest teepee on a snow-free morning. (Dr. Noorali Bharwani)
The world's tallest teepee on a snow-free morning. (Dr. Noorali Bharwani)

By the time this column is published, we may know the exact cause of death of Philip Seymour Hoffman, perhaps the most widely admired American actor of his generation. He was 46. How sad. He left behind three young children, their mother and millions of admiring grieving moviegoers.

The death is believed to be from an apparent drug overdose. Investigators found a syringe in his arm and, nearby, an envelope containing what appeared to be heroin. Heroin is highly addictive painkiller.

Charles Romley Alder Wright (1844 – 1894) was an English chemistry and physics researcher at St. Mary’s Hospital Medical School in London. He was the first person to synthesize heroin, in 1874. Heroin itself is an active drug, but it is also converted into morphine in the body.

Opium is obtained from the opium poppy. Opium contains approximately 12 per cent morphine, which is frequently processed chemically to produce heroin for the illegal drug trade and for legal medicinal use.

Heroin, when used in a medical environment, is referred to as diamorphine. It is highly addictive drug. According to the National Institute on Drug Abuse, heroin is both the most abused and the most rapidly acting of the opiates.

It is estimated Afghanistan, in 2004, produced roughly 87 per cent of the world supply in illicit raw opium. However, the production rate in Mexico has risen six-fold from 2007 to 2011, placing Mexico as the second largest opium producer in the world. Reports indicate Mexican cartels are also known to produce another type of illicit heroin, commonly called black tar.

A UN report last year put the problems in stark perspective. “The number of people who die of heroin overdoses in NATO countries per year (above 10,000) is five times higher than the total number of NATO troops killed in Afghanistan in the past eight years,” it said. “We need to go back to the dramatic opium addiction in China a century ago to find comparable statistics.”

Canadian police seized 92 kilograms of heroin in 2008, up from 67 kilograms in 2001 – a 38 per cent increase, according to Health Canada, which tests seized drugs for police forces. They also seized 67 per cent more raw opium. In Alberta, the police have seized 42 times more heroin and opium each year on average between 2002 and 2008 than in the 1995-2001 period.

Is there a solution to the problem?

It is almost impossible to get hold of the drug dealers at the “factory” level. The problem is almost worldwide. It is an epidemic, which cannot be controlled by vaccination. The best thing we can do is educating the public, especially our children, of the dangers of using drugs and the consequences of addiction. Prevention is better than cure. Pursuing healthy lifestyle includes avoiding drugs, no smoking, don’t drink and drive, exercise regularly, meditate and laugh a lot. A good family environment and good friends are the pillars of good health.

That’s it for this week. Talk to you again soon. Take care.

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Cancer Drugs are Being Abused by Bodybuilders

Kin Coulee Park, Medicine Hat: A beautiful mild evening look in January. (Dr. Noorali Bharwani)
Kin Coulee Park, Medicine Hat: A beautiful mild evening look in January. (Dr. Noorali Bharwani)

I was surprised when my attention was drawn to an article in MedPage Today titled “Bodybuilders Bulk Up Using… Cancer Drugs.” Should I be surprised?

“The only thing that should surprise us is that there are still some things that can surprise us,” said Francois de La Rochefoucauld (1613 – 1680). He was a noted French author with a clear-eyed, worldly view of human conduct that indulges in neither condemnation nor sentimentality.

Abusing cancer drugs to muscle up your body does call for condemnation. As we know, performance-enhancing drugs are substances used by athletes to improve their performances.

The phrase has been used to refer to several distinct classes of drugs: steroids, human growth hormone, stimulants (caffeine, amphetamine, methamphetamine), painkillers (simple analgesics to narcotics), sedatives, diuretics, blood boosters and others.

What about abuse of cancer drugs?

“Arimidex, also known by its chemical name anastrozole, is an aromatase inhibitor – a breast cancer drug. While steroids and growth hormone make headlines when athletes abuse them, breast cancer drugs are a lesser-known staple of doping regimens, for athletes and ‘weekend warriors’ alike,” says the article. Even common anti-estrogen breast cancer drugs like tamoxifen and exemestane are abused.

The article says these breast cancer drugs are on the prohibited performance-enhancing drugs lists from the U.S. Anti-Doping Agency and the World Anti-Doping Agency. But somehow some athletes manage to find them. How can this be stopped? A difficult question to answer.

Those athletes who abuse performance-enhancing drugs do eventually suffer from side effects. Hopefully, they will learn early in their lives that the best way to improve your health is by exercising regularly, eating healthy and not abusing performance-enhancing drugs. I hope somebody is listening.

Talk to you again soon. Keep smiling.

Start reading the preview of my book A Doctor's Journey for free on Amazon. Available on Kindle for $2.99!

Swine Flu Causes Anxiety in the General Population

A careful walk in the snow certainly helps to stay healthy. (Dr. Noorali Bharwani)
A careful walk in the snow certainly helps to stay healthy. (Dr. Noorali Bharwani)

The Canadian Lung Association has a logo on their website, “When you can’t breathe, nothing else matters.” That is a pretty serious situation. And that is what swine flu is doing in some parts of Canada.

The media report, as of few days ago, says the virus has claimed the lives of six people in Saskatchewan and 10 people in Alberta. It is also making its presence felt in southwestern B.C. By the time you read this the numbers may have changed.

Getting the flu vaccine is your best protection against H1N1 flu virus. The virus is contagious and infects the breathing tubes in your nose, throat, and lungs. It causes swine flu. Swine or pig flu is a form of influenza that affects pigs, or a form of human influenza that is caused by a related virus. You cannot get H1N1 from properly handled and cooked pork or pork products. People with regular exposure to pigs are at increased risk of swine flu infection.

Symptoms of H1N1 are similar to seasonal flu symptoms. Chills, fever, sore throat, muscle pains, severe headache, coughing, weakness and general discomfort. These symptoms usually come on quickly. If it’s difficult to breathe, then get emergency help right away.

If you have mild or moderate symptoms, stay home for seven to 10 days unless you need to see your doctor or go to emergency. Sleep a lot, drink lots of fluids and stay away from other people. Your doctor will decide if antivirals are right for you. It’s best to start antiviral medicines within the first two days of symptoms.

If your symptoms are getting worse then go straight to hospital emergency. The best way to prevent the H1N1 flu is to get the seasonal flu vaccine. And I hope you have done that.

That is all for today. Sleep well, listen to music, dance and eat healthy. “Human happiness and human satisfaction must come from within oneself. It is wrong to expect some final satisfaction to come from money or computer,” says Dalai Lama.

Start reading the preview of my book A Doctor's Journey for free on Amazon. Available on Kindle for $2.99!