Diarrhea

Diarrhea is a worldwide problem. It causes significant ill health and many people die. The situation is worse in poor countries. Even in developed countries diarrhea causes significant illness and death.

Diarrheal diseases have been a scourge to humanity throughout recorded history all over the world. “Infections are estimated to account for three to four billion cases of diarrhea each year, and up to 4.3 million deaths in children under the age of five years,” says an article in the Canadian Journal of Gastroenterology.

Diarrhea means loose, watery stools and abdominal cramps. Frequency of bowel movements may vary in each case.

Management of diarrhea depends on whether it is acute or chronic.

Acute diarrhea is unpleasant and almost everyone experiences at one time or another. The loose stools usually last a few days.

Most common causes of acute diarrhea are due to infections:

-Viruses: Rotavirus and adenovirus are common examples in young children. Direct contact easily spreads viral diarrhea.

-Bacteria and parasites: Parasites such as Giardia and cryptosporidium can cause diarrhea. Certain bacteria like campylobacter, salmonella, shigella and E. coli can cause diarrhea. The source of infection is contaminated food or water.

-Diarrhea can also be side effect of many medications, particularly antibiotics.

-Traveler’s diarrhea can occur in 20 to 50 percent of travelers to tropical countries. Eighty percent of traveler’s diarrhea is due to bacterial infection.

Chronic diarrhea lasts much longer than acute diarrhea. Diarrhea lasting four weeks would probably be considered chronic but six to eight weeks would provide a better distinction.

The prevalence of chronic diarrhea in the United States seems to be approximately five percent.

It can be a sign of a serious disorder like chronic infection, inflammatory bowel disease or poor absorption of nutrients (malabsorption). It may be due to a less serious condition such as irritable bowel syndrome.

Other causes of diarrhea are: Lactose, a sugar found in milk and milk products, artificial sweeteners, sorbitol and mannitol, found in chewing gum and other sugar-free products can cause diarrhea.

There are many more causes of chronic diarrhea. They cannot all be mentioned here. To name few more: dumping syndrome, celiac disease, chronic pancreatitis, antacids, alcohol use and diabetes.

In one study, 30 percent of the patients a definite cause of diarrhea was found. In 20 percent of the patients the cause was found to be in laxative and diuretic abuse. In 50 percent of the patients – no specific diagnoses was made. They were given the diagnoses of “functional” or “idiopathic” diarrhea.

Most significant complication of diarrhea is dehydration – as suggested by excessive thirst, dry mouth, little or no urination, severe weakness, dizziness or lightheadedness. This can be dangerous especially in children and the elderly. One should seek immediate medical help.

Viral diarrhea can be prevented by washing hands and encouraging your children to wash their hands. One must also guard against diarrhea caused by contaminated food and water.

Several precautions should be undertaken when one is traveling in tropical countries.

Investigation of diarrhea includes history and physical examination. Blood and stool tests. If no cause is found then examination of the colon, stomach and duodenum with an endoscope should be undertaken.

Sometimes diarrhea is only an inconvenience. Sometimes it can be life threatening. Sometimes it can be prevented by good preventive measures like washing hands and avoiding potentially contaminated food and water. Sometimes there is not much you can do to avoid it – especially in cases like ulcerative colitis, Crohn’s disease and other medical conditions.

So, if you have diarrhea then see your doctor before it runs you down!

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Influenza in Children

On November 21st, Dr. Paul Schnee, Medical Officer of Health for Palliser Health Region (PHR) sent a memo to Palliser Physicians and Staff on the subject of influenza. In the memo he indicates that five children have died in UK from influenza due to A/Fujian virus.

Dr. Schnee says, “As seen during previous influenza seasons, young children are the first to be affected. That is because most young children have little or no history of exposure to influenza viruses and have limited protective immunity.”

An article in the Canadian Medical Association Journal (CMAJ) says, “Each year, about 9-20 percent of healthy children aged less than five years will require health care for an influenza-related illness.”

So how can we protect our children from the scourge of influenza?

Current Canadian guidelines encourage vaccinating healthy young children but do not designate them as being at high risk of infection. In US, the current recommendation is that all healthy children aged six to 23 months should be given influenza immunization. This change came about recently. Can Canada do the same thing?

Children with influenza present with fever, with acute respiratory tract illness and with middle ear infection. Children under two years of age are very prone to complications like pneumonia and croup.

“The key to controlling influenza infection is prevention,” says the CMAJ article.

So how can we do that?

On November 18th, Dr. Schnee had sent a memo to Physicians and Staff of PHR titled, “Influenza information provided to the media”.

The memo contains a list of dos and don’ts which the general public should be aware of. It is well written. It is simple and easy to understand. I think it should be read by everybody.

If the PHR can afford it then a laminated copy of this memo (November 18th) should be delivered to every home in the region. It will be a good investment in preventive health. And the public will know how to make the best use of health care resources during the flu season.

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Lesbians and Cervical Cancer

Do lesbians get cervical cancer? Do they need Pap smear on regular basis?

This is a good question. Most people would think that lesbians do not get cervical cancer. That is not true.

This subject is discussed in an editorial in the British Medical Journal (BMJ) titled, “Health needs of women who have sex with women”. I will attempt to summarize it here.

The editorial starts by saying, “…..lesbian is a term that describes sexual identity. However, sexual identity does not necessarily predict sexual behavior—most lesbians have a history of sexual intercourse with men.”

We know that sexual intercourse with men is a powerful risk factor for cervical cancer. The virus responsible for developing changes in the cervix, which may eventually lead to cervical cancer, is called genital human papillomavirus. Studies have shown that one in five women who have never had heterosexual intercourse have human papillomavirus.

“Therefore regular testing of cervical (Pap) smears should be recommended to all women who have sex with women, regardless of their present or past sexual activities”, says the BMJ editorial.

Another condition is called “bacterial vaginosis”. This is more common in women who have sex with women than heterosexual women—it is found in up to half of women who have sex with women.

Sexually transmitted infections such as Chlamydia, gonorrhoea, and syphilis, are less common amongst women who have sex with women – but they are still at risk. The editorial says that overall more than 10 percent of women with exclusively female partners have a history of sexually transmitted infections.

Female to female sexual transmission of HIV has been reported. The editorial also briefly touches on other aspects of lesbian lifestyle which can affect lesbian’s mental and physical health.

Another article in the same issue of the BMJ provides online health information web links for lesbians. There are many sites. I will mention just two:

Health Canada site is: www.hcsc.gc.ca/english/women/facts_issues/lesbian_health.htm.

American Government site is: www.4woman.gov/faq/Lesbian.htm.

These sites offer guidance about the frequency with which lesbian women should have pap smears, screening for sexually transmitted infections, and mammograms.

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Bowel Cancer

How common is bowel cancer?

Cancer of the large bowel (colon and rectum) is the third common cause of death from cancer. Cancer of the small bowel (duodenum, jejunum and ileum) is quite rare.

In Palliser Health Region (PHR), about 44 new cases of colon and rectal cancers are diagnosed each year. And about 20 patients die from this disease each year.

The incidence of colon and rectal cancer between the ages of 20-49 years is less than 0.18 cases per 1000 population. Between 50-59 years of age, it is less than 0.66 cases per 1000 population. After this the incidence of colon and rectal cancer jumps from 1.74 cases/1000 population at 60 to 3.85 cases/1000 population at age 90.

According to the statistics published by the Alberta Cancer Board, the incidence and death rates for all cancers in PHR are similar to provincial rates. Exception being the female breast cancer incidence rate – it appears to be lower than the provincial rate.

The statistics also show that number of new cases of cancer (all cancers) among males in PHR is consistently higher than females.

What symptoms and signs one should look for?

Rectal bleeding is the most important symptom. It should never be ignored at any age. Most rectal bleeding is due to benign disease. But one can never be sure until the symptom has been investigated and cause of the bleeding is identified.

A person over 60 with rectal bleeding, anemia, weight loss, and mass in the abdomen or rectum probably has colon or rectal cancer – unless it can be proven otherwise.

Other symptoms of significance are: change in bowel habit, change in caliber of stool, and sense of incomplete defecation.

What investigations are required to check for colon and rectal cancer?

A good history and physical examination is very important in all patients. This includes a rectal examination. A blood test may be ordered to check if you are anemic. If there are bowel symptoms without obvious rectal bleeding then stool can be checked for hidden blood (fecal occult blood test – FOBT).

Further investigation depends on your age and risk factors. Patients with low risk factors can be investigated with a flexible sigmoidoscopy (a 60cm flexible instrument). Barium enema may become necessary in some patients. Patients with high risk factors require a colonoscopy (a 160 cm flexible instrument).

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