Important Things to Know About CPR (Cardio-Pulmonary Resuscitation)

Sunrise at Haleakala Volcano Summit in Maui, Hawaii. (Dr. Noorali Bharwani)
Sunrise at Haleakala Volcano Summit in Maui, Hawaii. (Dr. Noorali Bharwani)

“Bystander CPR is the most important predictor of survival from cardiac arrest,” says an article in the Canadian Medical Association Journal (CMAJ January 9, 2017).

The article is titled “Five Things to Know About Cardio-pulmonary Resuscitation.” Here is the summary.

1. Chest compressions – importance of fast pushes

Chest compressions during CPR should be fast pushes. In adult patients with out-of-hospital cardiac arrest, a large multicentric study has shown patient survival to hospital discharge was highest when compressions were between 100 and 120 per minute.

2. During the use of a defibrillator – importance of peri-shock pauses

During cardiac arrest the heart needs to be shocked with a defibrillator. To do this chest compression has to stop for a brief moment. This is called peri-shock pauses. Peri-shock pauses should be limited to improve survival. High priority is given to minimizing interruptions for chest compressions. It is recommended that total pre-shock and post-shock pauses in chest compressions be as short as possible.

Studies have shown survival is higher for those patients who received pre-shock pauses of less than 10 seconds and total peri-shock pauses of less than 20 seconds during CPR. Peri-shock pauses should be minimized during CPR by performing compressions while the defibrillator is charging.

3. Interrupted or continuous CPR strategy?

Bystander CPR is the most important predictor of survival from cardiac arrest. Any interruptions in chest compressions are associated with reduced blood flow and worse survival.

For this reason, and because ventilation (mouth to mouthing breathing) is a difficult skill to acquire for those who are not health care professionals, the guideline update recommends that members of the public provide uninterrupted continuous chest compressions.

Trained rescuers should provide 30 chest compressions that are interrupted by no more than 10 seconds to provide two ventilations (mouth to mouth breathing).

4. Role of medications during cardiac arrest

Should we use vasopressin or epinephrine during resuscitation? The aim is to improve return of spontaneous circulation and improve survival.

Vasopressin is a hormone. Its two primary functions are to retain water in the body and to constrict blood vessels to raise blood pressure.

Epinephrine, also known as adrenaline, is a hormone. It plays an important role in the fight-or-flight response of the body by increasing blood flow to muscles, output of the heart, pupil dilation, and blood sugar. As a medication it is used to treat a number of conditions, including anaphylaxis, cardiac arrest, and superficial bleeding.

The CMAJ article says vasopressin offers no advantage over epinephrine in cardiac arrest.

There is limited evidence to suggest that vasopressin and epinephrine can improve return of spontaneous circulation. Because simplicity is important during resuscitation efforts, the guideline update specifically recommends that epinephrine be administered as soon as possible following onset of cardiac arrest.

5. Maintain patient’s temperature during cardiac arrest

A target temperature should be maintained in the post-cardiac arrest period.

All adult patients who are comatose with return of spontaneous circulation following cardiac arrest should receive targeted temperature management. The guideline update recommends selecting and achieving a single target temperature between 32°C and 36°C, which should be maintained constantly for at least 24 hours.

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Women with Breast Cancer Can Modify Their Lifestyle to Improve Prognosis

Sunrise at the World's Tallest Tepee, Medicine Hat, Alberta. (Dr. Noorali Bharwani)
Sunrise at the World's Tallest Tepee, Medicine Hat, Alberta. (Dr. Noorali Bharwani)

“Although more than 90 per cent of patients with breast cancer have early stage disease at diagnosis, about 25 per cent will eventually die of distant metastasis,” says an article in the Canadian Medical Association Journal (CMAJ February 21, 2017).

Women with breast cancer would like to improve their prognosis and live long. Making positive lifestyle changes can improve long-term prognosis and be psychologically beneficial, since the feeling of loss of control is one of the biggest challenges of a cancer diagnosis.

So which lifestyle changes can be recommended to patients in addition to standard breast cancer treatments?

The CMAJ article reviews the role of lifestyle factors, particularly weight management, exercise, diet, smoking, alcohol intake and vitamin supplementation, on the prognosis of patients with breast cancer. Here is the summary.

Weight management

Weight gain during or after breast cancer treatment increases the risk of recurrence and reduces survival, irrespective of baseline body mass index (BMI). Patients who are obese or overweight at breast cancer diagnosis have a poorer prognosis. So lose weight.

Physical activity

Physical activity can reduce breast cancer mortality by about 40 per cent and has the most powerful effect of any lifestyle factor on breast cancer outcomes. At least 150 minutes per week (about 30 minutes a day) of physical activity is recommended, but less than 13 per cent of patients with breast cancer attain this. So exercise more.

Diet

Western-style diets (high in processed grains, processed meats and red meat) and prudent diets (high in fruits, vegetables, whole grains and chicken) have similar rates of breast cancer recurrence. Diets rich in saturated fat, especially from high-fat dairy products, may be associated with increased breast cancer deaths. Soy products have not been found to increase breast cancer recurrence and may actually reduce it. Eat less and stop eating fatty food.

Smoking

Recent evidence has shown a strong association between a history of smoking and breast cancer mortality. Women who quit smoking after diagnosis of breast cancer have higher overall survival and possibly better breast cancer–specific survival. So quit smoking.

Alcohol intake

Findings are too inconsistent to conclude that alcohol consumption affects breast cancer outcomes. However, limiting alcohol consumption to one or fewer drinks per day reduces the risk of a second primary breast cancer.

Vitamin supplementation

Moderate increases in dietary vitamin C or oral supplementation may reduce breast cancer mortality, but randomized trials are needed to confirm these findings. Vitamin E supplementation is not associated with breast cancer outcomes. Low levels of vitamin D at diagnosis have been associated with an increased risk of breast cancer deaths. However, randomized trials are needed to determine whether supplementation improves prognosis. One multivitamin a day and Vitamin D 2000 units a day is good for your health.

So the message is clear – make positive life-style changes like exercise more, lose weight and eat healthy. And keep smiling.

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Self-Monitoring of Blood Glucose in Diabetes

A tree in Maui. (Dr. Noorali Bharwani)
A tree in Maui. (Dr. Noorali Bharwani)

Diabetes mellitus or simply called diabetes is a chronic, lifelong condition that affects our body’s ability to use the energy found in food. This happens when our body’s capacity to produce insulin is diminished.

There are two types of diabetes – not counting gestational diabetes that occurs during pregnancy.

Type 1 diabetes is usually diagnosed in children and young adults, and was previously known as juvenile diabetes. Only five per cent of people with diabetes have this form of the disease. The body is not capable of producing insulin.

Type 2 diabetes is the most common form of diabetes. In this situation the body produces insulin but the body does not use insulin properly. Eventually, the pancreas that normally produces insulin fails.

Individuals with diabetes have to check the blood sugar levels regularly to make sure it is within normal range. If the levels are too high then it can cause many complications. Instead of going to a lab for blood tests diabetic patients can now do their own blood tests and adjust their own insulin dosage.

Consumer Report (Blood Glucose Meter Buying Guide) says today’s blood glucose meters are smaller, faster, and come with more features than ever before. They’re also more accurate than blood glucose meters of years past. That’s good news for approximately 30 million North Americans with diabetes.

Why is it so important for diabetics to monitor their blood sugar levels?

Controlling blood glucose is key to managing diabetes and preventing complications. Test results help patients make adjustments to their diet, exercise routine, and diabetes treatment plan, which can help lower the risk of seizures, blindness, kidney disease, and nerve damage. There are dozens of models available priced between $10 and $75.

The Consumer Report warns don’t just look at the retail price of the meters alone. What makes blood glucose monitoring expensive is the test strips that you might use many times a day. At $18 to $184 per 100 test strips, the cost can add up to about $265 to $2,685 a year for people who test four times a day. Also there is a learning curve to make sure you get a full value for your health and investment.

Does regular monitoring of your blood sugar make your health better?

Xiang and colleagues (Journal of Diabetes Science and Technology, July 2014) says the blood glucose meter is the most successful and widely used portable device for point-of-care tests. The device has more than 50 years of technology development. So the device has stood the test of time. Regular self-monitoring of blood glucose levels in diabetics play a key role in preventing complications in the short, medium and long term.

How do you decide which meter to buy?

One way is to ask your friends who have similar health issues. Ask your doctor, nurse, dietician or individuals who work in diabetic clinics. See what the Consumer Reports has to say. Experts at their National Testing and Research Center tested 25 models to see which ones perform best.

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Doctors advised to treat elderly carefully with cholesterol-lowering drugs (statins).

Dubai, United Arab Emirates. (Dr. Noorali Bharwani)
Dubai, United Arab Emirates. (Dr. Noorali Bharwani)

The College of Physicians and Surgeons of Alberta in their newsletter, The Messenger (Jan 11 2017) advised doctors to use statins carefully in the elderly.

If your blood cholesterol level is high then you should ask your doctor if treatment with statins is right for you.

High cholesterol level is a risk factor for heart disease. Statins are drugs that can lower cholesterol level in your blood. If your blood cholesterol level is high then plaques build up on the blood vessel walls. This causes partial or complete blockage of the blood vessels and reduces or blocks blood circulation. Why would you want that to happen?

Statin drugs are commonly used to reduce blood cholesterol level. Examples of statins include – atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastatin (Crestor) and simvastatin (Zocor).

Statin is effective in lowering the cholesterol level. It may have other health benefits but we do not know everything about it. What is the effect of statin in the elderly is not very well known either. There is a variable quantity of data related to statin use in the elderly, according to the Canadian Cardiovascular Society Guidelines (2016).

The 2016 guidelines continue to recommend treatment for individuals at high risk for cardio-vascular events. This is with the caveat that for adults older than age 75 who are otherwise robust, a discussion should take place regarding the risks and benefits in the context of their individual situation. As I said earlier we do not have much information on the side effects of statin in individuals over the age of 75.

What are the side effects of statin use?

The most common adverse events (1.3 per cent) identified include musculoskeletal events (aches and pains in the muscles) and elevation in liver enzymes. Although not statistically significant, there may be new-onset diabetes and cataract formation. Doctors should monitor their patients for cognitive impairment as well, as it may be associated with statin use.

If you have been on statin prior to age 65, then you can continue to take it after that age if you have had no side effects. Make sure you discuss this with your doctor. You should try to keep total cholesterol level below 6.22 mmol/L. LDL or “bad” cholesterol should be below 3.37 mmol/L.

Taking a statin is one thing but you have to remember lifestyle changes are essential for reducing your risk of heart disease, whether you take a statin or not.

To reduce your risk: 1. Quit smoking and avoid second hand smoke. 2. Eat a healthy diet that’s low in saturated fat, trans fat, refined carbohydrates and salt, and rich in fruits, vegetables, fish, and whole grains. 3. Be physically active, sit less and exercise regularly. 4. Maintain a healthy waist girth: less than 40 inches in men and less than 35 inches in women.

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