Author: noorali

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Are you constipated?

Chronic constipation is a very common problem. I see patients with stomach and bowel problems all the time and constipation is high on their list of complaints. Usually, it has been present for many years. We usually tell patients with chronic constipation to take high fiber diet, do regular exercise and drink plenty of fluids. But what really works for constipation?

Let us start by defining what chronic constipation is. Unfortunately, there is no simple definition. Most people complain of constipation if they do not have a bowel movement for a few days or if they have difficulty emptying. Generally speaking, constipation is defined as having a bowel movement fewer than three times a week. The bowel movements are usually hard, dry, and small in size.

We do not need a daily bowel movement to be healthy. We do not have to spend money on bowel cleansing with laxatives and enemas to get rid of so called toxins. Daily bowel movements are not important for overall health.

As part of my research for this column, I came across an article in the American Journal of Medicine (AJM) titled: Constipation in the Primary Care Setting: Current Concepts and Misconceptions. The article reviews what works and what does not work in patients with chronic constipation. Here are some important points discussed in the article.

Regular exercise, high fiber diet and fluids are good choices for a healthy life style. But if one of these choices is missing in your life then it would not be a major factor in causing chronic constipation.

High fiber diet increases stool weight and frequency in healthy individuals and decreases the time it takes for the stool to travel to the rectum. Increase intake of fiber has shown to help some chronically constipated individuals. High fiber diet does not help patients who have irritable bowel syndrome where constipation is the dominant symptom, patients who have slow large bowel transit time or have problem with emptying the rectum due to muscle weakness. That means all constipated patients will not benefit from high fiber diet.

What about fluid intake and exercise? The article says that adequate fluid intake and regular exercise improves general health but there is no evidence to support the use of these measures in treating constipation

What about the laxatives? Laxatives are among the most widely used medications in Western countries, says the AJM article. Laxatives are designed to increase the frequency and ease of bowel movement. They are easily accessible and sometimes abused as most of them can be purchased over-the-counter. There are three categories of laxatives:
-Bulk agents: psyllium, methylcellulose, Calcium polycarbophil
-Osmotic agents: polyethylene glycol, lactulose, sorbitol, glycerine suppositories magnesium citrate, magnesium sulfate
-Bowel stimulants: bisacodyl, senna

Bulk agents like psyllium work in similar fashion to high fiber diet. Studies have shown that osmotic laxatives like lactulose, sorbitol and polyethylene glycol are effective. Stimulant laxatives are also effective in many patients with constipation, although certainly not all. Except for bloating and flatulence, laxatives have few side effects. Once daily dosage should be encouraged for better compliance. There is no evidence to support the belief that stimulant laxatives like senna can damage colonic nerves if chronically used.

The article says that although tolerance to laxatives has not been studied extensively in humans, it seems to be uncommon in the majority of laxative users. Tolerance to stimulant laxatives occurs in patients who have constipation due to slow transit time and whose colons have poor neurological function. Can you get addicted, habituated or dependent on laxatives? The answer is no. Most laxatives are not absorbed in the system so there is no risk of addiction.

So, high fiber diet, adequate fluid intake, regular exercise and psyllium should work for most patients with chronic constipation. If you are resistant to these measures then you can add something like lactulose or a stool softener. If that does not work then add senna.

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An Angel with Ovarian Cancer

Recently, an angel was diagnosed with ovarian cancer. She is 87-years-old. I have known her for many years. She is an angel because she is kind, she is generous, she is caring and she believes in miracles. She has been an excellent wife, mother and grandmother. She lost her husband 17 years ago but managed to survive in Canada without speaking any English. She is one tough lady.

But now her time is up. Doctors have said her prognosis is poor. Once cancer has spread it is usually a losing battle. But how long the battle will last is anybody’s guess. In the meantime my angel is wasting away – slowly and sometimes painfully. Her sprit is high but the energy level is low. What keeps her going is her family and friends. Some of them have flown from all over the world. They are here to say thanks for the memories and good-bye. They want to pay their last respects.

Each year, about 2400 Canadian women or angels are diagnosed with ovarian cancer. Sadly, 1700 women with the disease die each year. In North America, ovarian cancer is the second most common gynecologic malignant disease and is the leading cause of death among women with gynecologic cancer.

Why do so many women die of ovarian cancer? More than 60 per cent of the women are in advanced stage when first diagnosed. Their five year survival rate is less than 30 per cent. Their prognosis is poor and they have very few treatment options. Some studies have reported higher survival rates of greater than 90 per cent in women with stage one disease. Only 25 per cent of the women are diagnosed early.

Is there anyway we can detect ovarian cancer early? In early stages symptoms are usually non-specific and vague, but as the disease progresses they may include abdominal distention or pain, change in bowel and/or bladder habits, and gynecologic complaints such as pain during intercourse. Pelvic examination does not help in early cases but generally detect ovarian cancer that is at an advanced stage. So, early diagnosis is difficult.

There have been several studies to examine the efficacy of routine ultrasound and screening using blood test CA125 for early detection. Unfortunately, these techniques have not been clearly shown to be effective for early detection. Therefore, there is no recommendation to use ultrasound or CA125 blood test for screening.

There are two risk factors for ovarian cancer: first, 10 per cent of women with ovarian cancer have a family history of the same disease and second, a much larger group includes postmenopausal women who are over 50 years of age, in whom 90 per cent of ovarian cancer occurs sporadically.

One study suggests that women who do not have regular medical check-ups or pelvic examinations and who have no regular family physician or health care provider are at increased risk of ovarian cancer. The authors of the study say that although the exact mechanism of this association is unknown, women, especially those who are postmenopausal, should be encouraged to maintain regular medical care. Women who are found to have benign diseases of the ovary are also thought to be at a higher risk for ovarian cancer.

Many aspects of ovarian cancer are poorly understood. So screening is not currently recommended for the general population. There are a number of trials going on which may give us answers in the future. But this may take many years.

For now, there isn’t much good news for women in general and my angel in particular. I hope she does not suffer for too long. Some days pain and vomiting is unbearable. Some days things are not bad. I worry and have sleepless nights about my angel because she is precious and she is my mother.

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The Truth About Omega-3 Fatty Acids

On a regular basis, we read about the benefits of eating fish and consuming omega-3 fatty acids. We have been told that there is epidemiologic data showing the beneficial effects a diet rich in fish oils can have on cardiovascular disease.

Recently, the Canadian Medical Association Journal (CMAJ) published several articles on this subject. The main theme of the articles was to see if there is a scientific evidence to show fish oils are beneficial for patients with heart disease and if fish oils prevent any kind of chronic disease.

Reports suggest that an average typical Western diet has omega-3 fatty acids found in fish to be about 150 mg per day. This is equivalent to eating about one fish meal every 10 days. This is not enough. The general recommendation is 650 mg per day of omega-3 fatty acids..

The American Heart Association recommends that people without coronary heart disease have two fish meals each week (at least 300 mg of omega-3 fatty acids daily), and they recommend that patients with documented coronary heart disease receive 1000 mg daily.

Omega-3 fatty acids are DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid). These are considered essential fatty acids as our body does not make them and we have to obtain them from food or commercially marketed pills.

There are three sources of omega-3 fatty acids: the most important source is fish (e.g. salmon, tuna, and trout) which has long chain fatty acids DHA and EPA. Some foods like eggs, dairy products and yogurt are fortified with omega-3 fatty acids. Second source is plants (which has short chain fatty acid alpha-linolenic acid)and plant oils, including leafy vegetables, walnuts, mustard seed oil, soy bean oil, canola oil and flaxseed oil (which is made up of 50 per cent alpha-linolenic acid). The third source is commercially available salmon and flax seed oil pills. Fish oil capsule 1000 mg has 300 to 600 mg of DHA and EPA.

It is important to remember that plant omega-3 fatty acids are not the same as fish omega-3 fatty acids. Chemically they are similar but they are metabolized in the body differently. Our bodies can convert about five per cent of -linolenic acid to EPA.

How do omega-3 fatty acids help us?

DHA and EPA are thought to confer their cardiac protective effects by making the blood less likely to form clots, lowering triglycerides (fat in the blood) and protecting against irregular heartbeats that can cause sudden cardiac death. However, the results of all studies have not been consistent. Besides, we don’t know as much about the effects of plant omega-3 fatty acids, but they appear to have similar actions in reducing coronary heart disease events, says one of the articles in the CMAJ.

Medical literature suggests omega-3 fatty acids from fish may reduce cardiac deaths, inflammatory disease, including rheumatoid arthritis and ulcerative colitis, and promote brain development and mental function. Generally speaking, there are no risks in taking omeg-3 fatty acids.

A 2006 review of hundreds of studies on fish and health concluded that eating one to two servings each week is enough to reduce the risk of dying from heart attack by 36 per cent.

Should patients with cardiovascular disease take fish oil? An article in the CMAJ by Nair and Connolly says three randomized controlled trials failed to convincingly demonstrate a beneficial effect of omega-3 fatty acids in preventing ventricular arrhythmia (irregular heart rhythm) and cardiovascular death.

Health Canada currently does not approve omega-3 fatty acids for prevention of cardiovascular outcomes, says the article and there is insufficient evidence to recommend the routine use of omega-3 fatty acids. In spite of these conclusions by Nair and Connolly, many experts believe that taking omega-3 fatty acids may lead to a general increase in the overall health and well-being of the population.

Finally, remember omega-3 fatty acids are not panacea for all kinds of health problems. . Regular exercise and healthy eating is important part of staying healthy.

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Happiness and Good Health

Almost everybody I know wants to be happy and healthy. As somebody has said, happiness is man’s greatest aim in life. In 2005, a British study showed that happiness and health may overlap. That means we should continue to strive to be happy if we want to be healthy.

How do you define happiness? Happiness can mean different things to different people. And what exactly makes men and women happy? Is it the materialist extreme searching for happiness in external conditions or is it the spiritual extreme claiming that happiness is the result of a mental state? It seems research supports both the materialist and the mentalist positions, later has the stronger findings.

Although human sciences recognize that happiness is the fundamental goal of life, there is a very limited understanding of what happiness itself consists of. With the tremendous technological advance in the western countries people believed that materialism, longevity, healthy life, acquisition of wealth and ownership of consumer goods would lead to happiness. But wealthy people are not necessarily happy or healthy people.

You may wonder why I thought of this subject at this time of the year. During the Christmas holidays I was in Disneyland, California with my family. This was my sixth visit to the Mickey land and third one with my family. And we have been once to Disneyworld in Orlando as well. Call me nuts if you like but I am a big Mickey and Pluto fan and I am very happy when I am in Disneyland with my family. It is the most carefree happy holiday I can have. Plus it is a healthy one as we walk a lot. Three days in Disneyland, one day at Universal Studios and one day in Los Angeles and Hollywood makes it a worthwhile happy trip.

Disneyland is promoted as the happiest place in the world. For me it is. Last time we were there in 1992 and 1993 when my children were six and four years old. Their memory is pretty foggy of what they did in 1993. So they wanted to go there again and have fun and be happy and healthy. My wife and I were ready to oblige. And that is what we did. That is my kind of happiness. Of course there are many other things which make me happy. I can produce a long list of things which make me happy each day.

Amazing thing about Disneyland is that they take their responsibility of making people happy very seriously. We stayed at one of their hotels and we did not have one complain. The service was excellent. In the park itself, there are hundreds or thousands of helpers to guide you and make your day a happy one. The long lines keep moving and you don’t even realize you have been in the line for an hour. The new system of Fastpass works quite well. I am really impressed the way they manage to keep every body smiling and happy all the time. It is amazing. Can we do the same for our family and friends and strangers we meet each day?

While I was having fun and being happy in Disneyland, I am sure there were people all over the world doing other things that made them happy. And that begs the question: What makes happy people happy? You must have noticed that happy people have a different attitude, they interpret the world in a different way and they are not complainers or whiners. Their glass is always half full not half empty. They are not materialistic in nature.

Why is happiness important? Studies have shown that happier people are generally healthier people – not only mentally, but also physically. Happiest people have lower levels of the stress hormone cortisol. Their hearts keep a mellower pace than those of less happy people, and they don’t flip out as much during a mental stress test.

So, the message is simple: If you want to be healthy then be happy, don’t worry and hug Mickey once day!

Start reading the preview of my book A Doctor's Journey for free on Amazon. Available on Kindle for $2.99!